Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dual Specificity Phosphatase 6 (DUSP6) Polymorphism Predicts Prognosis of Inoperable Non-Small Cell Lung Cancer after Chemoradiotherapy.

Clinical laboratory - 1 Jan 2016

Wang Tian-Lu, Song Ying-Qiu, Ren Yang-Wu, Zhou Bao-Sen, Wang He-Tong, Bai Lu, Zhang Hai-Bo, Yu Hong, Zhao Yu-Xia

Abstract excerpt

BACKGROUND: Dual-specificity phosphatase 6 (DUSP6) inactivates different target kinases to regulate cell proliferation and differentiation. Altered DUSP6 expressions or gene polymorphisms are associated with human cancer development including non-small cell lung cancer (NSCLC). DNA topoisomerase II alpha (TOP2A) regulates chromosome condensation and chromatid separation, and altered TOP2A expressions are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Non-Small-Cell Lung

Share to Chemoradiotherapy

Share to Lung Neoplasms

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Share to Proportional Hazards Models

Source

Identifiers

PMID: 27156317
DOI: 10.7754/clin.lab.2015.150432

Genes

DUSP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dual Specificity Phosphatase 6 (DUSP6) Polymorphism Predicts Prognosis of Inoperable Non-Small Cell Lung Cancer after Chemoradiotherapy.PMID 27156317Read ↗

Association of Topoisomerase II (TOP2A) and Dual-Specificity Phosphatase 6 (DUSP6) Single Nucleotide Polymorphisms with Radiation Treatment Response and Prognosis of Lung Cancer in Han Chinese.Semantic proximity Read ↗

Dual-specificity phosphatase 6 genetic variants associated with risk of lung squamous cell carcinoma in Han Chinese.Semantic proximity Read ↗

NPAS2 dampens chemo-sensitivity of lung adenocarcinoma cells by enhancing DNA damage repairSemantic proximity Read ↗

USP14 Regulates DNA Damage Response and Is a Target for Radiosensitization in Non-Small Cell Lung CancerSemantic proximity Read ↗

KIAA0101 and UbcH10 interact to regulate non-small cell lung cancer cell proliferation by disrupting the function of the spindle assembly checkpointSemantic proximity Read ↗

Dual-specific phosphatase 5 (DUSP5), upregulated in lung adenocarcinoma, as a potential therapeutic target for lung cancer.Semantic proximity Read ↗

SGOL1 variant B induces abnormal mitosis and resistance to taxane in non-small cell lung cancers.Semantic proximity Read ↗

Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype.Semantic proximity Read ↗

Mining expression and prognosis of topoisomerase isoforms in non-small-cell lung cancer by using Oncomine and Kaplan–Meier plotterSemantic proximity Read ↗

ASPM induces radiotherapy resistance by disrupting microtubule stability leading to chromosome malsegregation in non-small cell lung cancerSemantic proximity Read ↗

In vitro sensitivity to platinum-derived drugs is associated with expression of thymidylate synthase and dihydropyrimidine dehydrogenase in human lung cancer.Semantic proximity Read ↗

Wee1 epigenetically modulates H2B mono‐ubiquitination at K120 lysine and DNA double‐strand break repair through phosphorylation of H2BY37 ‐dependent manner in small‐cell lung cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.