Article

KIAA0101 and UbcH10 interact to regulate non-small cell lung cancer cell proliferation by disrupting the function of the spindle assembly checkpoint

2020-09-28

Abstract excerpt

<h4>Background: </h4> Chromosome mis-segregation caused by spindle assembly checkpoint (SAC) dysfunction during mitosis is an important pathogenic factor in cancer, and modulating SAC function has emerged as a potential novel therapy for non-small cell lung cancer (NSCLC). UbcH10 is considered to be associated with SAC function and the pathological types and clinical grades of NSCLC. KIAA0101, which contains a hig...

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Literature Corpus work: 6a69d1c7-cba7-5ec3-8a10-616bad374059
DOI: 10.21203/rs.3.rs-15900/v3

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