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NPAS2 dampens chemo-sensitivity of lung adenocarcinoma cells by enhancing DNA damage repair

30 Jan 2024

Abstract excerpt

Chemotherapeutic agents, including cisplatin, have remained a cornerstone of lung adenocarcinoma (LUAD) treatment and continue to play an essential role in clinical practice, despite remarkable progress in therapeutic strategies. Hence, a thorough comprehension of the molecular mechanisms underlying chemotherapeutic agent resistance is paramount. Our investigation centered on the potential involvement of the...

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PMID: 38291048
DOI: 10.1038/s41419-023-06256-3

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