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Article

Mutations of NKX2.5 and GATA4 genes in the development of congenital heart disease.

Gene - 15 Aug 2016

Tong Yi-Fan

Abstract excerpt

OBJECTIVE: To investigate the mutations of NKX2.5 and GATA4 genes in the development of CHD in Chinese population. METHODS: Between December 2010 and December 2014, 185 cases of CHD patients and 210 cases of healthy people were enrolled. NKX2.5 and GATA4 gene mutations and gene expression were detected via DNA sequencing and real-time PCR (RT-PCR), respectively. BMSCs were transfected with pCMV-HA-NKX2.5 and...

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Share to Cell Differentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeobox Protein Nkx-2.5

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Share to Myocytes, Cardiac

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Source

Identifiers

PMID: 27154817
DOI: 10.1016/j.gene.2016.04.061

Genes

GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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