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Article

Identification of functional mutations in GATA4 in patients with congenital heart disease.

PloS one - 1 Jan 2013

Wang Erli, Sun Shuna, Qiao Bin, Duan Wenyuan, Huang Guoying, An Yu, Xu Shuhua, Zheng Yufang, Su Zhixi, Gu Xun, Jin Li, Wang Hongyan

Abstract excerpt

Congenital heart disease (CHD) is one of the most prevalent developmental anomalies and the leading cause of noninfectious morbidity and mortality in newborns. Despite its prevalence and clinical significance, the etiology of CHD remains largely unknown. GATA4 is a highly conserved transcription factor that regulates a variety of physiological processes and has been extensively studied, particularly on its role...

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Source

Open in PubMed Open full text

Identifiers

PMID: 23626780
DOI: 10.1371/journal.pone.0062138
PMCID: PMC3633926

Genes

GATA4
TBX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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