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Article

Association of NKX2‐5, GATA4, and TBX5 polymorphisms with congenital heart disease in Egyptian children

4 Mar 2019

Abstract excerpt

BACKGROUND: Several genes encoding transcription factors are known to be the primary cause of congenital heart disease. NKX2-5 and GATA4 were the first congenital heart disease-causing genes identified by linkage analysis. This study designed to study the association of five single-nucleotide variants of NKX2-5, GATA4, and TBX5 genes with sporadic nonsyndromic cases of a congenital cardiac septal defect in...

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PMID: 30834692
DOI: 10.1002/mgg3.612

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