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Article

Gene Interactions Provide Evidence for Signaling Pathways Involved in Cleft Lip/Palate in Humans.

Journal of dental research - 1 Oct 2016

Velázquez-Aragón J A, Alcántara-Ortigoza M A, Estandia-Ortega B, Reyna-Fabián M E, Méndez-Adame C D, González-Del Angel A

Abstract excerpt

Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common craniofacial birth defect that has a complex etiology. Genome-wide association studies have recently identified new loci associated with NSCL/P, but these loci have not been analyzed in a Mexican Mestizo population. A complex etiology implies the presence of genetic interactions, but there is little available information regarding this in...

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Source

Identifiers

PMID: 27154735
DOI: 10.1177/0022034516647034

Genes

ABCA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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