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Article

Association of single nucleotide polymorphisms in the IRF6 gene with nonsyndromic cleft lip with or without cleft palate in Kinh Vietnamese patients.

Molecular biology reports - 1 Feb 2023

Phan Hoanh Duy Ba, Phuong Lam Hoai, Dang Tran Ngoc, Tram Duong Bich, Vu Hoang Anh

Abstract excerpt

BACKGROUND: The interferon regulatory factor 6 (IRF6) gene, which causes Van der Woude syndrome, is associated with nonsyndromic cleft lip with or without cleft palate (NSCL/P). Single nucleotide polymorphisms (SNPs) in the IRF6 gene were identified as susceptibility indicators of this defect in several populations. To further evaluate its role in this birth defect, we conducted this study with the aim of...

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PMID: 36484949
DOI: 10.1007/s11033-022-08164-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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