Article
Association among IRF6 polymorphism, environmental factors, and nonsyndromic orofacial clefts in western china.
DNA and cell biology - 1 May 2009
Jia Zhong-Lin, Li Yang, Li Ling, Wu Jun, Zhu Lu-Ying, Yang Chao, Chen Chun-Hui, Shi Bing
Abstract excerpt
The interferon regulatory factor 6 (IRF6) gene and environmental factors have been shown to be associated with nonsyndromic cleft lip with or without cleft palate (NSCL/P) in several populations. This study aimed to confirm the contribution of IRF6 and environmental factors to NSCL/P risk in western Han Chinese. Five single nucleotide polymorphisms (SNPs) were investigated in 107 case trios (child and parents)...
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