Article
Variation at HLA-DPB1 is associated with dermatomyositis in Chinese population.
The Journal of dermatology - 1 Nov 2016
Zhang Chang-E, Li Yang, Wang Zai-Xing, Gao Jin-Ping, Zhang Xiao-Guang, Zuo Xian-Bo, Sheng Yu-Jun, Chen Gang, Sun Liang-Dan, Zhang Xue-Jun, Xu Jin-Hua, Yang Sen
Abstract excerpt
Dermatomyositis (DM) is a polygenic disorder characterized by inflammation of skeletal muscle and skin. To date, the exact etiopathogenesis of DM remains elusive. To explore the genetic basis of DM, we conducted genome-wide genotyping analysis of 127 patients and 1566 healthy controls by Illumina Human OmniZhongHua-8 BeadChips in the Chinese Han population. We investigated whether the three SNP (rs7750458,...
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