Article
HLA class II alleles may influence susceptibility to adult dermatomyositis and polymyositis in a Han Chinese population.
BMC dermatology - 4 Jun 2014
Gao Xiang, Han Lei, Yuan Lan, Yang Yongchen, Gou Guimei, Sun Hengjuan, Lu Ling, Bao Liming
Abstract excerpt
BACKGROUND: Polymyositis (PM) and dermatomyositis (DM) are idiopathic inflammatory myopathies. Genetic variability in human leukocyte antigen (HLA) genes plays an important role in the pathogenesis of PM and DM. However, few studies on the subject in Chinese populations have been reported thus far. METHODS: We studied the influence of HLA polymorphisms on DM and PM susceptibility by analyzing HLA-DRB1, HLA-DQA1,...
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