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Article

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma

1 Apr 2016

Abstract excerpt

Large-scale genomic characterization of tumors from prospective cohort studies may yield new insights into cancer pathogenesis. We performed whole-exome sequencing of 619 incident colorectal cancers (CRCs) and integrated the results with tumor immunity, pathology, and survival data. We identified recurrently mutated genes in CRC, such as BCL9L, RBM10, CTCF, and KLF5, that were not previously appreciated in this...

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PMID: 27149842
DOI: 10.1016/j.celrep.2016.03.075

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