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An immunogenomic stratification of colorectal cancer: Implications for development of targeted immunotherapy

4 Mar 2015

Abstract excerpt

Although tumor infiltrating lymphocyte (TIL) density is prognostic and predictive in colorectal cancer (CRC), the impact of tumor genetics upon colorectal immunobiology is unclear. Identification of genetic factors that influence the tumor immunophenotype is essential to improve the effectiveness of stratified immunotherapy approaches. We carried out a bioinformatics analysis of CRC data in The Cancer Genome...

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Cancer Immunotherapy and Biomarkers
Ferroptosis and cancer prognosis
Genetic factors in colorectal cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25949894
DOI: 10.4161/2162402x.2014.976052

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