Article
The epithelial-mesenchymal transition phenotype of metastatic lymph nodes impacts the prognosis of esophageal squamous cell carcinoma patients.
Oncotarget - 21 Jun 2016
Wen Jing, Luo Kong-Jia, Liu Qian-Wen, Wang Geng, Zhang Mei-Fang, Xie Xiu-Ying, Yang Hong, Fu Jian-Hua, Hu Yi
Abstract excerpt
Epithelial-mesenchymal transition (EMT) plays a key role in tumor metastasis, but the significance of EMT phenotype to the prognosis of esophageal squamous cell carcinoma (ESCC) patients remains unclear. We used immunohistochemistry to examine the expression of the EMT-related proteins E-cadherin, N-cadherin and vimentin in samples of T3N1-3M0 ESCC from 155 primary tumors (PTs) with paired metastatic lymph nodes...
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