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Article

Epithelial circulating tumor cells with a heterogeneous phenotype are associated with metastasis in NSCLC.

Journal of cancer research and clinical oncology - 1 May 2022

Zhang Yujuan, Men Yu, Wang Jianyang, Xing Puyuan, Zhao Jun, Li Junling, Xu Danfei, Hui Zhouguang, Cui Wei

Abstract excerpt

OBJECTIVES: To analyze the clinical relevance of heterogeneous phenotypes of peripheral circulating tumor cells (CTCs) in non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: CTCs in 5 mL venous blood were enriched using the Canpatrol™ CTC technique in 82 NSCLC patients. And then, CTCs were subjected to RNA in situ hybridization with a combination of epithelial (EpCAM and CK8/18/19) and mesenchymal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34255149
DOI: 10.1007/s00432-021-03681-9
PMCID: PMC9016037

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