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Epithelial-mesenchymal transition phenotypes of circulating tumor cells correlate with the clinical stages and cancer metastasis in hepatocellular carcinoma patients.

Cancer biomarkers : section A of Disease markers - 6 Dec 2017

Chen Jing, Cao Shun-Wang, Cai Zhen, Zheng Lei, Wang Qian

Abstract excerpt

BACKGROUND: Epithelial-mesenchymal transition (EMT) plays a crucial role in circulating tumor cells (CTCs) dissemination and cancer metastasis. OBJECTIVE: To investigate the EMT phenotypes of CTCs in hepatocellular carcinoma (HCC) patients and the clinical utility in the early diagnosis of HCC metastasis and progression. METHODS: We retrospectively analyzed the count and EMT classification of CTCs detected by the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28869439
DOI: 10.3233/CBM-170315

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AFP

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