Article
Classification of epithelial-mesenchymal transition phenotypes in esophageal squamous cell carcinoma is strongly associated with patient prognosis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2011
Sung Chang Ohk, Park Cheol-Keun, Kim Seok-Hyung
Abstract excerpt
Epithelial-mesenchymal transition is characterized by a loss of cell adhesion and increased cell mobility due to cells gaining a mesenchymal phenotype. During the epithelial-mesenchymal transition process, tumor cells are expected to lose their epithelial phenotype and gradually and sequentially acquire a mesenchymal phenotype. Epithelial-mesenchymal transition is a dynamic and reversible process, which has been...
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