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Article

The co-stimulatory molecule B7-H3 promotes the epithelial-mesenchymal transition in colorectal cancer.

Oncotarget - 31 May 2016

Jiang Bo, Zhang Ting, Liu Fen, Sun Zhangzhang, Shi Hanping, Hua Dong, Yang Chen

Abstract excerpt

B7-H3, first recognized as a co-stimulatory molecule, is abnormally expressed in cancer tissues and is associated with cancer metastasis and a poor prognosis. However, as an initial event of metastasis, the relationship between the Epithelial-Mesenchymal Transition (EMT ) in cancer cells and B7-H3 has still not been investigated. In this study, we first analyzed B7-H3 expression by immunohistochemistry in...

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Source

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Identifiers

PMID: 27145365
DOI: 10.18632/oncotarget.9035
PMCID: PMC5077974

Genes

MMP2
MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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