Article
B7H1 Expression and Epithelial-To-Mesenchymal Transition Phenotypes on Colorectal Cancer Stem-Like Cells.
PloS one - 1 Jan 2015
Zhi Yidan, Mou Zhirong, Chen Jun, He Yujun, Dong Hui, Fu Xiaolan, Wu Yuzhang
Abstract excerpt
Cancer stem cells (CSCs) can invade and metastasize by epithelial-to-mesenchymal transition (EMT). However, how they escape immune surveillance is unclear. B7H1 is crucial negative co-stimulatory molecule but little information about whether it works in CSCs. Therefore, we determined the expression of B7H1 and EMT-associated markers in colorectal cancer stem-like cells to investigate a possible immunoevasion way...
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