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Article

B7-H3 and its relevance in cancer immunological and non-immunological perspectives

1 Jan 2011

Abstract excerpt

B7-H3 is a transmembrane glycoprotein and a member of the B7 family of proteins. It was previously known as an immunoregulatory molecule, shown in recent years to be of clinical significance in different types of cancer. In some tumor types high expression of B7-H3 has been linked to a poor prognosis, whereas in other cancers the opposite effect has been observed. Taken together, the precise role of B7-H3 in...

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PMID: 21622107
DOI: 10.2741/e304

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