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Article

Preferential Expression of B7‐H6 in Glioma Stem‐Like Cells Enhances Tumor Cell Proliferation via the c‐Myc/RNMT Axis

1 Jan 2020

Abstract excerpt

B7 homologue 6 (B7‐H6), a newly identified member of the B7 costimulatory molecule family, is not only a crucial regulator of NK cell‐mediated immune responses through binding to NKp30 but also has clinical implications due to its abnormal expression in human cancers. Here, we show that B7‐H6 expression is abnormally upregulated in glioma tissue and that B7‐H6 is coexpressed with stem cell marker Sox2....

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Identifiers

PMID: 32322592
DOI: 10.1155/2020/2328675

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