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Article

The novel non‐immunological role and underlying mechanisms of B7‐H3 in tumorigenesis

21 Jun 2019

Abstract excerpt

B7 homolog 3 (B7-H3) has been proven to be involved in tumorigenesis. An elucidation of its role and underlying mechanisms is essential to an understanding of tumorigenesis and the development of effective clinical applications. B7-H3 is abnormally overexpressed in many types of cancer and is generally associated with a poor clinical prognosis. B7-H3 inhibits the initiation of the "caspase cascade" by the Janus...

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PMID: 31222741
DOI: 10.1002/jcp.28936

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