Article
Organ identity specification factor WGE localizes to the histone locus body and regulates histone expression to ensure genomic stability in Drosophila.
Genes to cells : devoted to molecular & cellular mechanisms - 1 May 2016
Ozawa Nao, Furuhashi Hirofumi, Masuko Keita, Numao Eriko, Makino Takashi, Yano Tamaki, Kurata Shoichiro
Abstract excerpt
Over-expression of Winged-Eye (WGE) in the Drosophila eye imaginal disc induces an eye-to-wing transformation. Endogenous WGE is required for organ development, and wge-deficient mutants exhibit growth arrest at the larval stage, suggesting that WGE is critical for normal growth. The function of WGE, however, remains unclear. Here, we analyzed the subcellular localization of WGE to gain insight into its...
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