Article
In vivo analysis of Drosophila SU(Z)12 function.
Molecular genetics and genomics : MGG - 1 Feb 2008
Chen Sa, Birve Anna, Rasmuson-Lestander Asa
Abstract excerpt
Polycomb group (PcG) proteins are required to maintain a stable repression of the homeotic genes during Drosophila development. Mutants in the PcG gene Supressor of zeste 12 (Su(z)12) exhibit strong homeotic transformations caused by widespread misexpression of several homeotic genes in embryos and larvae. Su(z)12 has also been suggested to be involved in position effect variegation and in regulation of the white...
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