Article
Drosophila histone locus bodies form by hierarchical recruitment of components.
The Journal of cell biology - 16 May 2011
White Anne E, Burch Brandon D, Yang Xiao-Cui, Gasdaska Pamela Y, Dominski Zbigniew, Marzluff William F, Duronio Robert J
Abstract excerpt
Nuclear bodies are protein- and RNA-containing structures that participate in a wide range of processes critical to genome function. Molecular self-organization is thought to drive nuclear body formation, but whether this occurs stochastically or via an ordered, hierarchical process is not fully understood. We addressed this question using RNAi and proteomic approaches in Drosophila melanogaster to identify and...
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