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Dynamics of Mutations during Development of Resistance by Pseudomonas aeruginosa against Five Antibiotics.

Antimicrobial agents and chemotherapy - 1 Jul 2016

Feng Yanfang, Jonker Martijs J, Moustakas Ioannis, Brul Stanley, Ter Kuile Benno H

Abstract excerpt

Pseudomonas aeruginosa is an opportunistic pathogen that causes considerable morbidity and mortality, specifically during intensive care. Antibiotic-resistant variants of this organism are more difficult to treat and cause substantial extra costs compared to susceptible strains. In the laboratory, P. aeruginosa rapidly developed resistance to five medically relevant antibiotics upon exposure to stepwise...

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PMID: 27139485
DOI: 10.1128/AAC.00434-16
PMCID: PMC4914676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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