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Article

A Mendelian Randomization Study of Plasma Homocysteine and Multiple Myeloma.

Scientific reports - 29 Apr 2016

Xuan Yang, Li Xiao-Hong, Hu Zhong-Qian, Teng Zhi-Mei, Hu Dao-Jun

Abstract excerpt

Observational studies have demonstrated an association between elevated homocysteine (Hcy) level and risk of multiple myeloma (MM). However, it remains unclear whether this relationship is causal. We conducted a Mendelian randomization (MR) study to evaluate whether genetically increased Hcy level influences the risk of MM. We used the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism as an...

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Identifiers

PMID: 27126524
DOI: 10.1038/srep25204
PMCID: PMC4850434

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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