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Article

Causal Effects of Homocysteine, Folate, and Cobalamin on Kidney Function: A Mendelian Randomization Study.

Nutrients - 11 Mar 2021

Park Sehoon, Lee Soojin, Kim Yaerim, Cho Semin, Kim Kwangsoo, Kim Yong Chul, Han Seung Seok, Lee Hajeong, Lee Jung Pyo, Joo Kwon Wook, Lim Chun Soo, Kim Yon Su, Kim Dong Ki

Abstract excerpt

Blood homocysteine level and related vitamin levels are associated with various health outcomes. We aimed to assess causal effects of blood homocysteine, folate, and cobalamin on kidney function in the general population by performing Mendelian randomization (MR) analysis. Genetic instruments for blood homocysteine, folate, and cobalamin levels were introduced from a previous genome-wide association (GWAS)...

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Identifiers

PMID: 33799553
DOI: 10.3390/nu13030906
PMCID: PMC8001564

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