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Article

Evidence on the causal link between homocysteine and hypertension from a meta-analysis of 40 173 individuals implementing Mendelian randomization.

Journal of clinical hypertension (Greenwich, Conn.) - 1 Dec 2019

Fu Liwan, Li Ya-Nan, Luo Dongmei, Deng Shufang, Wu Baihui, Hu Yue-Qing

Abstract excerpt

Numerous researchers have investigated the associations among methylenetetrahydrofolate reductase gene (MTHFR) C677T polymorphism, homocysteine (Hcy) concentration, and hypertension. However, the results are controversial. Thus, a meta-analysis implementing Mendelian randomization approach was conducted to examine the hypothesis that elevated Hcy concentration plausibly contributes to increased risk of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31769183
DOI: 10.1111/jch.13737
PMCID: PMC8030561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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