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Article

Causal relationships between inflammatory factors and multiple myeloma: A bidirectional Mendelian randomization study.

International journal of cancer - 15 Nov 2022

Wang Qiangsheng, Shi Qiqin, Lu Jiawen, Wang Zhenqian, Hou Jian

Abstract excerpt

Changes in serum inflammatory factors occur throughout the onset and multiple myeloma (MM) progression, the feedback loops make it harder to distinguish between causes and effects. In the present study, we performed a bidirectional summary-level Mendelian randomization (MR) analysis to elucidate the causal relationships of C-reactive protein (CRP) and inflammatory regulators with MM. Summary-level data of genetic...

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PMID: 35841389
DOI: 10.1002/ijc.34214

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