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Article

Association of homocysteine with type 2 diabetes: a meta-analysis implementing Mendelian randomization approach.

BMC genomics - 10 Dec 2013

Huang Tao, Ren JingJing, Huang Jinyan, Li Duo

Abstract excerpt

BACKGROUND: We tested the hypothesis that elevated homocysteine (Hcy) level is causally associated with increased risk of type 2 diabetes mellitus (T2DM). RESULTS: The meta-analysis and Mendelian randomization analysis were performed among 4011 cases and 4303 controls. The absolute pooled mean Hcy concentration in subjects with MTHFR 677TT was 5.55 μmol/L (95% CI, 1.33 to 9.77) greater than that in subjects with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24320691
DOI: 10.1186/1471-2164-14-867
PMCID: PMC3878883

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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