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Article

Klotho and the aging process.

The Korean journal of internal medicine - 1 Jun 2011

Kuro-o Makoto

Abstract excerpt

The klotho gene was originally identified as a putative age-suppressing gene in mice that extends life span when overexpressed. It induces complex phenotypes resembling human premature aging syndromes when disrupted. The gene was named after a Greek goddess Klotho who spun the thread of life. Since then, various functional aspects of the klotho gene have been investigated, leading to the identification of...

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Identifiers

PMID: 21716585
DOI: 10.3904/kjim.2011.26.2.113
PMCID: PMC3110841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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