Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence of Inbreeding in Hodgkin Lymphoma.

PloS one - 1 Jan 2016

Thomsen Hauke, Inacio da Silva Filho Miguel, Fuchs Michael, Ponader Sabine, Pogge von Strandmann Elke, Eisele Lewin, Herms Stefan, Hoffmann Per, Engert Andreas, Hemminki Kari, Försti Asta

Abstract excerpt

Genome-wide association studies (GWASs) have identified several, mainly co-dominantly acting, single-nucleotide polymorphisms (SNPs) associated with Hodgkin lymphoma (HL). We searched for recessively acting disease loci by performing an analysis of runs of homozygosity (ROH) based on windows of homozygous SNP-blocks and by calculating genomic inbreeding coefficients on a SNP-wise basis. We used data from a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Consanguinity
Share to Genes, Recessive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Genome, Human

Share to Germany

Share to Hodgkin Disease

Share to Reproduction

Share to Selection, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 27123581
DOI: 10.1371/journal.pone.0154259
PMCID: PMC4849743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence of Inbreeding in Hodgkin Lymphoma.PMID 27123581Read ↗

Inbreeding and homozygosity in breast cancer survival.Semantic proximity Read ↗

Discovery of novel predisposing coding and noncoding variants in familial Hodgkin lymphoma.Semantic proximity Read ↗

Genome-wide homozygosity signature and risk of Hodgkin lymphoma.Semantic proximity Read ↗

Runs of homozygosity and inbreeding in thyroid cancer.Semantic proximity Read ↗

Inbreeding coefficient estimation with dense SNP data: comparison of strategies and application to HapMap III.Semantic proximity Read ↗

Estimates of autozygosity derived from runs of homozygosity: empirical evidence from selected cattle populations.Semantic proximity Read ↗

The use of runs of homozygosity for estimation of recent inbreeding in Holstein cattle.Semantic proximity Read ↗

A whole-genome-based approach for estimation and characterization of individual inbreedingSemantic proximity Read ↗

A model-based approach to characterize individual inbreeding at both global and local genomic scales.Semantic proximity Read ↗

HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma SubtypesSemantic proximity Read ↗

FSuite: exploiting inbreeding in dense SNP chip and exome data.Semantic proximity Read ↗

Genomic consequences of intensive inbreeding in an isolated wolf population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.