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Genomic consequences of intensive inbreeding in an isolated wolf population.

Nature ecology & evolution - 1 Jan 2018

Kardos Marty, Åkesson Mikael, Fountain Toby, Flagstad Øystein, Liberg Olof, Olason Pall, Sand Håkan, Wabakken Petter, Wikenros Camilla, Ellegren Hans

Abstract excerpt

Inbreeding (mating between relatives) is a major concern for conservation as it decreases individual fitness and can increase the risk of population extinction. We used whole-genome resequencing of 97 grey wolves (Canis lupus) from the highly inbred Scandinavian wolf population to identify 'identical-by-descent' (IBD) chromosome segments as runs of homozygosity (ROH). This gave the high resolution required to...

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Genome
Inbreeding
Norway
Polymorphism, Single Nucleotide
Sweden

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PMID: 29158554
DOI: 10.1038/s41559-017-0375-4

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