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Article

Genome-wide homozygosity signature and risk of Hodgkin lymphoma.

Scientific reports - 22 Sept 2015

Sud Amit, Cooke Rosie, Swerdlow Anthony J, Houlston Richard S

Abstract excerpt

Recent studies have reported that regions of homozygosity (ROH) in the genome are detectable in outbred populations and can be associated with an increased risk of malignancy. To examine whether homozygosity is associated with an increased risk of developing Hodgkin lymphoma (HL) we analysed 589 HL cases and 5,199 controls genotyped for 484,072 tag single nucleotide polymorphisms (SNPs). Across the genome the...

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Identifiers

PMID: 26391888
DOI: 10.1038/srep14315
PMCID: PMC4585760

Genes

NFKB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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