Article
Inbreeding and homozygosity in breast cancer survival.
Scientific reports - 12 Nov 2015
Thomsen Hauke, Filho Miguel Inacio da Silva, Woltmann Andrea, Johansson Robert, Eyfjörd Jorunn E, Hamann Ute, Manjer Jonas, Enquist-Olsson Kerstin, Henriksson Roger, Herms Stefan, Hoffmann Per, Chen Bowang, Huhn Stefanie, Hemminki Kari, Lenner Per, Försti Asta
Abstract excerpt
Genome-wide association studies (GWASs) help to understand the effects of single nucleotide polymorphisms (SNPs) on breast cancer (BC) progression and survival. We performed multiple analyses on data from a previously conducted GWAS for the influence of individual SNPs, runs of homozygosity (ROHs) and inbreeding on BC survival. (I.) The association of individual SNPs indicated no differences in the proportions of...
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