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Article

Robust Lys63-Linked Ubiquitination of RIG-I Promotes Cytokine Eruption in Early Influenza B Virus Infection.

Journal of virology - 15 Jul 2016

Jiang Jingwen, Li Jing, Fan Wenhui, Zheng Weinan, Yu Meng, Chen Can, Sun Lei, Bi Yuhai, Ding Chan, Gao George F, Liu Wenjun

Abstract excerpt

UNLABELLED: Influenza A and B virus infections both cause a host innate immunity response. Here, we report that the robust production of type I and III interferons (IFNs), IFN-stimulated genes, and proinflammatory factors can be induced by influenza B virus rather than influenza A virus infection in alveolar epithelial (A549) cells during early infection. This response is mainly dependent on the retinoic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Influenza, Human

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Source

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Identifiers

PMID: 27122586
DOI: 10.1128/JVI.00549-16
PMCID: PMC4936144

Genes

TRIM25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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