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Article

Activation of duck RIG-I by TRIM25 is independent of anchored ubiquitin.

PloS one - 1 Jan 2014

Miranzo-Navarro Domingo, Magor Katharine E

Abstract excerpt

Retinoic acid inducible gene I (RIG-I) is a viral RNA sensor crucial in defense against several viruses including measles, influenza A and hepatitis C. RIG-I activates type-I interferon signalling through the adaptor for mitochondrial antiviral signaling (MAVS). The E3 ubiquitin ligase, tripartite motif containing protein 25 (TRIM25), activates human RIG-I through generation of anchored K63-linked polyubiquitin...

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Share to CARD Signaling Adaptor Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24466302
DOI: 10.1371/journal.pone.0086968
PMCID: PMC3900705

Genes

TRIM25
MAVS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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