Article
Caveolin-1 regulates corneal wound healing by modulating Kir4.1 activity.
American journal of physiology. Cell physiology - 1 Jun 2016
Zhang Chengbiao, Su Xiaotong, Bellner Lars, Lin Dao-Hong
Abstract excerpt
The expression of caveolin-1 (Cav1) in corneal epithelium is associated with regeneration potency. We used Cav1(-/-) mice to study the role of Cav1 in modulating corneal wound healing. Western blot and whole cell patch clamp were employed to study the effect of Cav1 deletion on Kir4.1 current density in corneas. We found that Ba(2+)-sensitive K(+) currents in primary cultured murine corneal epithelial cells...
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