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Article

Loss of NHE8 expression impairs ocular surface function in mice.

American journal of physiology. Cell physiology - 1 Jan 2015

Xu Hua, Zhao Yang, Li Jing, Wang Mingwu, Lian Fangru, Gao Minghong, Ghishan Fayez K

Abstract excerpt

Sodium/hydrogen exchanger (NHE) 8 is expressed at the apical membrane of the epithelial cells and plays important roles in neutral sodium absorption in the gastrointestinal tract and the kidney. It also has an important role in epithelial mucosal protection in the gastric gland and the intestine. Although NHE8 has broad tissue distribution, the precise location and the physiological role of NHE8 in the eye remain...

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Identifiers

PMID: 25377091
DOI: 10.1152/ajpcell.00296.2014
PMCID: PMC4281672

Genes

MMP9
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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