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Article

GluD2 Endows Parallel Fiber-Purkinje Cell Synapses with a High Regenerative Capacity.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Apr 2016

Ichikawa Ryoichi, Sakimura Kenji, Watanabe Masahiko

Abstract excerpt

UNLABELLED: Although injured axons usually do not regenerate in the adult CNS, parallel fibers (PFs) regenerate synaptic connections onto cerebellar Purkinje cells (PCs). In this study, we investigated the role of GluD2 in this regenerative process after PF transection using GluD2-knock-out (KO) mice. All dendritic spines on distal dendrites were innervated by PFs in sham-operated wild-type controls, whereas...

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Source

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Identifiers

PMID: 27122040
DOI: 10.1523/JNEUROSCI.0161-16.2016
PMCID: PMC6601726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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