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Article

The extreme C-terminus of GluRdelta2 is essential for induction of long-term depression in cerebellar slices.

The European journal of neuroscience - 1 Mar 2007

Kohda Kazuhisa, Kakegawa Wataru, Matsuda Shinji, Nakagami Ryoichi, Kakiya Naomasa, Yuzaki Michisuke

Abstract excerpt

Long-term depression (LTD) of parallel fibre (PF)-Purkinje cell synapses in the cerebellum is recognized as a cellular substrate of motor learning. Although the delta2 glutamate receptor (GluRdelta2) has been shown to be crucial for LTD, the mechanisms by which GluRdelta2 functions remain elusive. In this study, we developed a virus vector-based gene transfer approach to rescue impaired LTD in GluRdelta2-null...

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Identifiers

PMID: 17425562
DOI: 10.1111/j.1460-9568.2007.05412.x

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PSD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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