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Article

Role of the internal Shank-binding segment of glutamate receptor delta2 in synaptic localization and cerebellar functions.

Neuroscience letters - 12 Mar 2008

Yasumura Misato, Uemura Takeshi, Yamasaki Miwako, Sakimura Kenji, Watanabe Masahiko, Mishina Masayoshi

Abstract excerpt

Glutamate receptor (GluR) delta2 selectively expressed in cerebellar Purkinje cells (PCs) plays key roles in cerebellar long-term depression (LTD), motor learning and formation of parallel fiber (PF)-PC synapses. We have recently shown that the PDZ [postsynaptic density (PSD)-95/Discs large/zona occludens-1]-binding domain at the C-terminal, the T site, is essential for LTD induction and the regulation of...

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Identifiers

PMID: 18249497
DOI: 10.1016/j.neulet.2008.01.009

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PSD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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