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Article

ITD assembler: an algorithm for internal tandem duplication discovery from short-read sequencing data.

BMC bioinformatics - 27 Apr 2016

Rustagi Navin, Hampton Oliver A, Li Jie, Xi Liu, Gibbs Richard A, Plon Sharon E, Kimmel Marek, Wheeler David A

Abstract excerpt

BACKGROUND: Detection of tandem duplication within coding exons, referred to as internal tandem duplication (ITD), remains challenging due to inefficiencies in alignment of ITD-containing reads to the reference genome. There is a critical need to develop efficient methods to recover these important mutational events. RESULTS: In this paper we introduce ITD Assembler, a novel approach that rapidly evaluates all...

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Identifiers

PMID: 27121965
DOI: 10.1186/s12859-016-1031-8
PMCID: PMC4847212

Genes

FLT3
KIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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