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Article

ScanITD: Detecting internal tandem duplication with robust variant allele frequency estimation.

GigaScience - 1 Aug 2020

Wang Ting-You, Yang Rendong

Abstract excerpt

BACKGROUND: Internal tandem duplications (ITDs) are tandem duplications within coding exons and are important prognostic markers and drug targets for acute myeloid leukemia (AML). Next-generation sequencing has enabled the discovery of ITD at single-nucleotide resolution. ITD allele frequency is used in the risk stratification of patients with AML; higher ITD allele frequency is associated with poorer clinical...

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Identifiers

PMID: 32852038
DOI: 10.1093/gigascience/giaa089
PMCID: PMC7450668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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