Identification of a functional variant for colorectal cancer risk mapping to chromosome 5q31.1.

doi:10.18632/oncotarget.9298

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Article

Identification of a functional variant for colorectal cancer risk mapping to chromosome 5q31.1.

Oncotarget - 7 Jun 2016

Ke Juntao, Lou Jiao, Chen Xueqin, Li Jiaoyuan, Liu Cheng, Gong Yajie, Yang Yang, Zhu Ying, Zhang Yi, Tian Jianbo, Chang Jiang, Zhong Rong, Gong Jing, Miao Xiaoping

Abstract excerpt

Genome-wide association studies (GWASs) have established chromosome 5q31.1 as a risk locus for colorectal cancer (CRC). We previously identified a potentially regulatory single nucleotide polymorphism (SNP) rs17716310 within 5q31.1. Now, we extended our study with another independent Chinese population, functional assays and analyses of TCGA (The Cancer Genome Atlas) data. Significant associations between...

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PMID: 27177089
DOI: 10.18632/oncotarget.9298
PMCID: PMC5085221

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SMAD5

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