Article
Post genome-wide association studies functional characterization of prostate cancer risk loci.
BMC genomics - 1 Jan 2013
Jiang Junfeng, Cui Weirong, Vongsangnak Wanwipa, Hu Guang, Shen Bairong
Abstract excerpt
BACKGROUND: Over the last decade, genome-wide association studies (GWAS) have discovered many risk associated single nucleotide polymorphisms (SNPs) of prostate cancer (PCa). However, the majority of the associated PCa SNPs, including those in linkage disequilibrium (LD) blocks, are generally not located in protein coding regions. The systematical investigation of the functional roles of these SNPs, especially...
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