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Article

MiRNA expression profile of chronic lymphocytic leukemia patients with 13q deletion.

Leukemia research - 1 Jul 2016

Hernández-Sánchez María, Rodríguez-Vicente Ana E, Hernández José-Ángel, Lumbreras Eva, Sarasquete María-Eugenia, Martín Ana-África, Benito Rocío, Vicente-Gutiérrez Carlos, Robledo Cristina, Heras Natalia de Las, Rodríguez Juan-Nicolás, Alcoceba Miguel, Coca Alfonso García de, Aguilar Carlos, González Marcos, Hernández-Rivas Jesús-María

Abstract excerpt

Deletion 13q (13q-) is the most common cytogenetic aberration in chronic lymphocytic leukemia (CLL) and is associated with the most favorable prognosis as the sole cytogenetic abnormality. However, it is heterogeneous whereby CLL patients with higher percentages of 13q- cells (13q-H) have a more aggressive clinical course and a distinct gene expression profile. The microRNA (miRNA) expression profile of CLL gives...

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Source

Identifiers

PMID: 27111859
DOI: 10.1016/j.leukres.2016.04.008

Genes

BCL2
KRAS
MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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