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13q14 Deletion and Its Effect on Prognosis of Chronic Lymphocytic Leukemia

2 Aug 2021

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is the most common leukemia affecting adults. CLL results due to uncontrolled accumulation of B lymphocytes in the body with the clinical spectrum ranging from comparatively benign disease to an aggressive form. The disease pathogenesis lies in molecular genetics, the most common alteration being the deletion in the long arm of chromosome 13, at position 14 (13q14) region. This...

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PMID: 34522485
DOI: 10.7759/cureus.16839

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