Article
Constraints on the Genetic and Antigenic Variability of Measles Virus.
Viruses - 21 Apr 2016
Beaty Shannon M, Lee Benhur
Abstract excerpt
Antigenic drift and genetic variation are significantly constrained in measles virus (MeV). Genetic stability of MeV is exceptionally high, both in the lab and in the field, and few regions of the genome allow for rapid genetic change. The regions of the genome that are more tolerant of mutations (i.e., the untranslated regions and certain domains within the N, C, V, P, and M proteins) indicate genetic plasticity...
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